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Mild nausea and throwing up (vomiting).

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At the same time, off-label use has potentially negative consequences.

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The most important message for her doctor id that she is unable to eat and has constant nausea.

The protective effect of erythropoietin on the acute phase of corrosive esophageal burns in a rat model.

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In the third National Health and Nutrition Examination Survey, neither sex nor racial-ethnic group was independently associated with HCV infection.

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Other factors affecting the rate and extent of response include availability of iron stores, the baseline hematocrit, and the presence of concurrent medical problems.

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Recombinant human erythropoietin for the treatment of anemia in the myelodysplastic syndromes: A clinical and erythrokinetic assessment.

One aim of gene therapy research has been to deliver EPO genes to humans to treat their anaemia.

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Treatment of Anemia among Women with Chronic Kidney Disease in United States Outpatient Settings.

There is a need for a head-to-head trial to compare Darbepoetin to Epotin alfa to see which has the best therapeutic advantage.

Use of Erythropoiesis-Stimulating Agents in Patients With Anemia of Chronic Kidney Disease: Overcoming the Pharmacological and Pharmacoeconomic Limitations of Existing Therapies.

Further studies are needed to define the safety and gain in efficacy with use of low-dosage ribavirin therapy.

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Discuss specific use of drug and side effects with patient as it relates to treatment.

This class of drugs binds to an enzyme that is necessary for the HIV virus to reproduce.

The short-term use of erythropoetin-stimulating agents: impact on the biochemical recurrence of prostate cancer.

Relapse after treatment occurs in 20 - 35% of patients.

Food and Drug Administration announcement, June 26, 1989.

In such patients, treatment with erythropoietin has been shown to enhance the quality of life.

CE system to help students identify weaknesses and improve knowledge.

The proxy problem: Child report versus parent report in health-related quality of life research.

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Patients with a sudden loss of response (with severe anemia and a low reticulocyte count) should be evaluated for PRCA with associated neutralizing antibodies to erythropoietin; discontinue treatment (permanently) in patients with PRCA secondary to neutralizing antibodies to erythropoietin.

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Erythropoietin levels in heart failure after an acute myocardial infarction: Determinants, prognostic value, and the effects of captopril versus losartan.

Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away).

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Source: Annals of the Rheumatic Diseases.

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Shacter E, Temple R, Webber K, Winkle H: The FDA's assessment of follow-on protein products: A historical perspective.

Viral hepatitis transmission in ambulatory health care settings.

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Treatment of the Anemia of Progressive Renal Failure with Recombinant Human Erythropoietin.

Because the treatment options for every patient are different, guidelines are voluntary and are not meant to replace your physician's independent judgment.

To decrease these risks, as well as the risk of serious cardiovascular and thromboembolic reactions, use the lowest dose needed to avoid RBC transfusions.

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The review also showed that ESAs increase the risk of serious cardiovascular and thromboembolic events when they are administered to target higher hemoglobin levels (13.

Nevertheless, in vivo similarity assessment between mAb originator and biosimilar in terms of pharmacokinetics, pharmacodynamics and safety (including immunogenicity) is often tested first in clinical studies.

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Randomized, Open-label Study Comparing the Pharmacoeconomic (Time and Motion) Benefit of Mircera and Epoetin Alfa in Patients With Chronic Kidney Disease (Stage V) on Dialysis.

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