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Serious side effects can also occur, such as internal bleeding and psychiatric problems, and these may require immediate medical attention.

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Controlled-release (CR) Sinemet and immediate-release Sinemet are equally effective in treating the symptoms of PD, but some people prefer the controlled release version.

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Side effects, including an increased risk of involuntary movements (dyskinesias), mainly result from an enhanced levodopa effect.

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This medication contains two drugs: carbidopa and levodopa.

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No risk factors were identified that would predispose patients to have such adverse events with either treatment.

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The most common adverse reactions occurring in early Parkinson's disease when used without levodopa were somnolence, insomnia, nausea, constipation, dizziness, fatigue, asthenia, hallucinations, dry mouth, muscle spasms, and peripheral edema.

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The suggested starting dosage for most patients taking more than 1500 mg of levodopa is one tablet of SINEMET 25-250 three or four times a day.

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All these effects are enhanced 2-6 fold by pre-treatment with carbidopa.

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The physician may also ask if symptoms are present in any close family members, since it is common for RLS to run in families and this type is sometimes more difficult to treat.

Make sure to use the medication along with food in case your health care practioner has directed you to do so).

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Use your prescribed amount at regular interval to maintain a stable quantity of the medicine in the body constantly.

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Any of the following symptoms should alert the practitioner that the patient may have aspiration pneumonia.

However, global ratings of improvement as assessed by both patient and physician were better during therapy with Sinemet CR than with SINEMET.

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Keep in mind that drugs used to treat primary RLS do not cure the condition, but only relieve symptoms.

DBS is a poor procedure to rescue someone with end stage Parkinson's disease who is wheelchair bound or in a nursing home, although these are the most desperate patients.

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Today, the majority of PD cases are effectively treated with a combination of medications, including the drug levodopa; however, the degenerative effects of PD will still eventually lead to the progressive deterioration of neuromuscular control affecting bodily functions and activities of daily living.

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