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In their lawsuit, while all the generic companies excluding Apotex conceded that their versions infringed upon Crestor's patent, they claimed that the patent covered an obvious variation of earlier compounds.

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These drugs work by decreasing fluid () production in the eye and now are often prescribed as an adjunct to or in combination with prostaglandins.

Serious damage to the eye and subsequent loss of vision may result from using contaminated ophthalmic solutions.

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