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In their lawsuit, while all the generic companies excluding Apotex conceded that their versions infringed upon Crestor's patent, they claimed that the patent covered an obvious variation of earlier compounds.

Last year's dip was due to a number of widely-used brand-name drugs losing patent protection, the report notes, and forecasts that low rates of growth in prescription drug spending, and hospital expenditures, will continue this year.

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These drugs work by decreasing fluid () production in the eye and now are often prescribed as an adjunct to or in combination with prostaglandins.

Serious damage to the eye and subsequent loss of vision may result from using contaminated ophthalmic solutions.

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