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Patients in our study who had ezetimibe added to pre-existing statin therapy experienced on average a 22 percent decrease in their LDL cholesterol levels; however, we found that in these patients, atherosclerosis progressed at a rate of four percent per year over the two-year study period.

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Recently, a large randomized trial in type 1 diabetic patients with nocturnal hypoglycemia reported that sensor-augmented insulin pump therapy with the threshold-suspend feature reduced nocturnal hypoglycemia, without increasing glycated hemoglobin values ().

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This study was not designed to compare treatment groups for infrequent events.

Ezetimibe is rapidly metabolized to ezetimibe-glucuronide in humans.

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Blending of ezetimibe with starch alone results in some agglomeration of ezetimibe ( FIG.

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Ezetimibe is a cholesterol-lowering drug that inhibits intestinal absorption of cholesterol and structurally related plant sterols across the intestinal wall.

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